Datasite offers real-time collaboration, and Q&A modules that are highly useful in due diligence processes. Investment bankers can answer queries very efficiently in real time with team members and other stakeholders.
Intralinks: Intralinks is more about collaborative complex deals, where it has an elaborate Q&A section with permission controls, and collaborative workflows. It comes with "auto-indexing" where files are organized effectively, and it saves much time.

Datasite: Datasite offers the M&A project management ability, task assignment, and timelines. It tracks in real time activities, it manages permission and organizes deal documents.
Intralinks: Intralinks has highly similar workflow capabilities such as user management underneath permissions, as well as track change history, and all users' activities. The ability of the Deal Team Management is effective for any deal that requires the involvement of any large, multi-party.